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Some paper on genome-wide association studies  

2010-10-12 22:56:17|  分类: 默认分类 |  标签: |举报 |字号 订阅

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A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal
A navigator for human genome epidemiology
A network view of disease and compound screening
A new statistical screening approach for finding pharmacokinetics-related genes in genome-wide studies
Evaluation of genome-wide association study results through development of ontology fingerprints
Association of three genetic loci with uric acid concentration and risk of gout
Gene expression profiling in rheumatoid arthritis
A decade of genome-wide gene expression profiling in acute myeloid leukemia
A future of cancer prevention and cures
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1
Cancer-Identifying drug–genotype interactions
Cell cycle, CDKs and cancer-a changing paradigm
Challenges and Opportunities in Defining the Essential Cancer
Cistromics of hormone-dependent cancer
Clinical Impact of High-Throughput Gene Expression Studies in Lung Cancer
Clinically Available Pharmacogenomics Tests
Combinatorial algorithms for structural variation detection in high-throughput sequenced genomes
Combinatorial patterns of somatic gene mutations in cancer
Common 5p15.33 and 6p21.33 variants influence lung cancer risk
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations
Complicated Supercomplexes
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Control Selection Options for Genome-Wide Association Studies
Defining the blueprint of the cancer genome
Dense genome-wide SNP linkage scan in 301 hereditary prostate cancer families identifies multiple regions with suggestive evidence for linkage
Differences in Genome Content among Helicobacter pylori Isolates from Patients with Gastritis, Duodenal Ulcer, or Gastric Cancer
DLC1-a significant GAP in the cancer genome
DNA variations in human and medical genetics
Epigenetic inheritance during the cell cycle
epigenome interactions in cancer
Evidence of genome-wide G4 DNA-mediated gene expression in human cancer cells
From cancer genomes to cancer models
From genes to function-the next challenge to understanding multiple sclerosis
Gene-Environment Interaction in Genome-Wide Association Studies-
Generating Genome-Scale Candidate Gene Lists for Pharmacogenomics
Genetic Susceptibility to Cancer
Genome profiling of acute myelomonocytic leukemia
genome-breast cancer genome-wide association study
Genome-Wide Analysis of Survival in Early-Stage Non–Small-Cell Lung Cancer
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
Genome-Wide Association Studieson RNAi
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1
Genome-wide profiling of genetic alterations in acute lymphoblastic leukemia-recent insights and future directions
Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies
Integrated Genome-Wide DNA Copy Number and Expression Analysis Identifies Distinct Mechanisms of Primary Chemoresistance in Ovarian Carcinomas
Lung cancer susceptibility locus at 5p15.33
Marker selection for genetic case–control association studies
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer
MicroRNA involvement in the pathogenesis and management of breast cancer
mouse model-enhanced genotypes, systemic phenotyping and envirotype modelling
Multiple loci identified in a genome-wide association study of prostate cancer
Multiple newly identified loci associated with prostate cancer susceptibility
New insights into the aetiology of colorectal cancer from genome-wide association studies
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2
Parallel progression of primary tumours and metastases
Predictive Biomarkers in the Development of Oncology Drugs
Predictive diagnosis of the cancer prone Li–Fraumeni syndrome by accident-new challenges through whole genome array testing
Progress and challenges in genome-wide association studies in humans
Prostate Cancer Genome-Wide Association Studies in Multiple Populations
Sequence variant on 8q24 confers susceptibility to urinary bladder cancer
Silent Polymorphisms Speak-How They Affect Pharmacogenomics and the Treatment of Cancer
Surveying the Genomic Landscape of Colorectal Cancer
The cancer genome
The HLA genomic loci map-expression, interaction, diversity and disease
The origins of bladder cancer
Transcriptome sequencing to detect gene fusions in cancer
Whole Genome Comparison of Allelic Imbalance between Noninvasive and Invasive Small-Sized Lung Adenocarcinomas
Common Genetic Variation and Human Traits
Copy number variants, diseases and gene expression
Copy-number variation in control population cohorts
A genetic framework for improving arrhythmia therapy
Association of a Polymorphism in the Lipin 1 Gene With Systolic Blood Pressure
Associations with myocardial infarction of six polymorphisms selected from a three-stage genome-wide association study
bp-Blood pressure control-salt gets under your skin
Cardiovascular Genetics and Genomics for the Cardiologist
Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels—The Framingham Heart Study
Current status of genome-wide scanning for hypertension
diabetes-Type 2 diabetes-new genes, new understanding
Genetic susceptibility to myocardial infarction and coronary artery disease
Genetic Variations in Nitric Oxide Synthase 1 Adaptor Protein Are Associated With Sudden Cardiac Death
Genetics and pathophysiology of arterial stiffness
Genetics of cardiac repolarization
Genetics of Cardiovascular Diseases
Genetics of Intracranial Aneurysms
Genetics of Type 1A Diabetes
Genomewide Association Analysis of Coronary Artery Disease
Genome-wide association of early-onset myocardial infarction
Genome-wide association study for type 2 diabetes
Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease
Genome-wide scan identifies variation in associated with plasma triglycerides
Genomics in cardiac metabolism
H NMR metabonomics approach to the disease continuum of diabetic complications and premature death
hp-Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor
Hypertension and genome-wide association studies
Identification of CELSR1 as a susceptibility gene for ischemic stroke
Is Obesity Our Genetic Legacy
LDL-cholesterol concentratioa genome-wide association study
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
MicroRNAs and cardiac pathology-
Monogenic Diabetes in the Young, Pharmacogenetics and Relevance to Multifactorial Forms of Type 2 Diabetes
Newly identified loci that influence lipid concentrations and risk of coronary artery disease
Plasma lipoproteigenetic influences and clinical implications
Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events
Prediction of Cardiovascular Disease Outcomes and Established Cardiovascular Risk Factors by Genome-Wide Association Markers
Rare independent mutations in renal salt handling genes contribute to blood pressure variation
Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
The Genetic Architecture of Intracerebral Hemorrhage
The search for new cardiovascular biomarkers
Translating molecular discoveries into new therapies for atherosclerosis
Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks
Data sharing in genomics — re-shaping scientific practice
Detecting genetic responses to environmental change
drug-Clinically Available Pharmacogenomics Tests
drug-Generating Genome-Scale Candidate Gene Lists for Pharmacogenomics
drug-Genome-wide association studies-progress and potential for drug discovery and development
drug-New insights into the genetics of addiction
epigenetics genome
Epigenomics
eQED-an efficient method for interpreting eQTL associations using protein networks
Evaluation of coverage variation of SNP chips for genome-wide association studies
From genotypes to genometypes-putting the genome back in genome-wide association studies
Genetic architecture of quantitative traits in mice, flies, and humans
Genetic Mapping in Human Disease
Genetic Mapping in Human Disease
Genetic Risk Prediction — Are We There Yet
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
Genome-wide Analysis of Alternative Pre-mRNA Splicing
Genome-wide analysis of DNA methylation patterns
Genomewide Association Studies — Illuminating Biologic Pathways
Genomewide Association Studies and Human Disease
Genome-wide association studies for complex traits
Genomewide Association Studies of Stroke
Genome-wide discovery of functional transcription factor binding sites by comparative genomics
Genomic approaches to small molecule discovery
Genomic medicine in Mexico
Genomics and genome-wide association studies-An integrative approach to expression QTL mapping
Genotype–phenotype databases
gi-Genome-wide association studies reach hepatology
Global analysis of mRNA splicing
Heritability in the genomics era — concepts and misconceptions
Human genetic variation and its contribution to complex traits
Autophagy genes in immunity
Functional variants in the B-cell gene are associated with systemic lupus erythematosus
Genetic susceptibility to SLE
The complex genetics of multiple sclerosis
The genetics of SLE-an update in the light of genome-wide association studies
The genetics of chronic inflammatory diseases
Is there still a need for candidate gene approaches in the era of genome-wide association studies
Letting the Genome out of the Bottle — Will We Get Our Wish
Long non-coding RNAs-insights into functions
Metabolic Enzymes as Oncogenes or Tumor Suppressors
method-biomarker-The parametric response map is an imaging biomarker for early cancer treatment outcome
method-Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens
Molecular genetics of human pigmentation diversity
Moving AHEAD with an international human epigenome project
Network-based global inference of human disease genes
New insights into the genetics of addiction
Next-generation DNA sequencing
A neurologist's guide to genome-wide association studies
Autism and other developmental brain disorders
Autism-Current Developments in the Genetics of Autism
Genome-wide association studies in neurological disorders
Psychiatric Genetics
Whole-genome association study of bipolar disorder
Wide Association Studies in Alzheimer Disease
The search for genes contributing to endometriosis risk
Pathway and network-based analysis of genome-wide association studies in multiple sclerosis
Pharmacogenetics in drug discovery and development
PTEN-a new guardian of the genome
renal-strategies for identifying genes involved in renal disease
respir-Discovering susceptibility genes for asthma and allergy
RNA-Seq-a revolutionary tool for transcriptomics
rug-Predictive Biomarkers in the Development of Oncology Drugs
Epigenetic regulation of stem cell fate
Genetic programming of liver and pancreas progenitors-lessons for stem-cell differentiation
Multiple layers of molecular controls modulate self-renewal and neuronal lineage specification of embryonic stem cells
Sequence variants at the locus associate with many cancer types
Singleton SNPs in the human genome and implications for genome-wide association studies
SNP genotyping-six technologies that keyed a revolution
SNP imputation in association studies
Splicing regulation
Structural Genomic Variation and Personalized Medicine
Systems genetics of complex traits
The road to genome-wide association studies
The search for alternative splicing regulators
The success of the genome-wide association approach
Validating, augmenting and refining genome-wide association signals
What Genome-wide Association Studies Can Do for Medicine
What would you do if you could sequence everything
wide association studies-Successful design and conduct of genome-wide association studies
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